A chronic inflammatory disease of unknown origin that affects the entire digestive tract from the mouth to the anus. It can develop in any part of the digestive tract, especially in the small and large intestine, and the patients are mainly young people. I. Symptoms The most common symptoms are abdominal pain, diarrhea, nutritional disorders and consequent weight loss, fever, etc. Anal lesions such as blood in the stool, hemorrhoids, perianal tumors, and anal fissures are a major feature. Abdominal pain and diarrhea are caused by abnormal proliferation of bacteria in the intestine and abnormal movement of the small and large intestine, resulting in decreased digestion and absorption, which in turn leads to nutritional disorders, weight loss, anemia, etc. The rise in blood CRP, sialic acid and alpha 2 globulin values is very effective in detecting the activity of Crohn’s disease, and the rise in platelets is sometimes seen during the active phase. x-ray examination can reveal fistulas and longitudinal ulcers in the colon. Endoscopic examination of the colon reveals various inflammatory conditions with mucosal bulges, narrowing and narrowing of the intestinal canal. The rectum of patients with Crohn’s disease may also show lesions, but sometimes the surface mucosa may appear normal. In contrast, ulcerative colitis will definitely show rectal lesions, which is a major difference between the two, so it is important to observe the rectum in order to distinguish between the two diseases. Biopsy may reveal inflammation accompanied by granulomas. Third, treatment Nutritional therapy to break down sugars and proteins into small molecules before giving is preferred, and fatty substances are strictly avoided. Drug therapy The etiology of Crohn’s disease is unknown, but it is generally believed to be due to immune abnormalities, so it can be treated with immunosuppressive agents, paracorticosteroids, etc. Surgery Since the recurrence rate after surgery is very high, resection needs to be limited to a minimum.