The most common cases of bumps on the waist that are a little painful to press are lipomas, fibroids, and sebaceous cysts. Usually this condition can be pressed to, are not too deep, lipomas and fibroids are more likely, this condition is related to the accumulation of fat. If stimulation or pressure may cause pain, it is necessary to check the ultrasound and not to deliberately stimulate. Attention should also be paid to whether there is local redness, heat, swelling, blood and oozing, and whether there is pus exudation, because sebaceous cysts or lipomas can sometimes be accompanied by infection. After this condition is caused, you need to disinfect with iodophor and apply topical Bactrim. If the condition persists without relief, you need to go to a regular hospital, have the wound cleared and disinfected, and have the medication changed regularly. The lump needs to be examined and an ultrasound or MRI done. If you are still not sure, you can remove it and send it to the pathology, which is more accurate. Do not stimulate it all the time and avoid squeezing it with your belt. If the enlargement is faster or the pain is more serious, it needs to be removed and sent to the pathology in time.