The causes of swelling of the face when patients get up from bed are commonly due to two diseases: the first is heart disease, where cardiac insufficiency causes restricted blood return, resulting in the formation of local swelling. The common area of swelling is usually the face, resulting in the phenomenon of swelling of the face when you wake up. This is because the capillaries in the face are richer and the blood vessels are finer, and blood pools in the face, thus causing swelling. Secondly, it may be caused by kidney disease. Kidney disease can also lead to renal insufficiency, and its main clinical manifestation is the presence of water and sodium retention, which causes local edema. It is also normal for patients to have facial edema due to water sinking in the body during sleep, which may also be accompanied by swelling in other areas, such as both lower limbs. It is recommended to go to the hospital in a timely manner, conduct relevant examinations, and after a clear diagnosis, actively carry out treatment to avoid serious complications.