Fracture 50 days is still swollen, may be related to the body’s own protective reaction due to the release of a variety of inflammatory factors, if the fracture occurs in the lower limbs, but also with the lower limbs of the venous or lymphatic reflux obstruction. After the body suffers from trauma, due to its own protective reaction will release a variety of inflammatory factors, these factors on the one hand will lead to an imbalance in fluid exchange between inside and outside the blood vessels, fluid overpenetration into the tissue interstitial space, resulting in limb swelling; on the other hand, it will also stimulate the nerves to release pain signals, the pain reflex will cause muscle spasms, resulting in venous and lymphatic reflux obstruction, resulting in tissue edema. If the fracture occurs in the lower extremity, the resistance to venous return is less than when the patient is lying on his back for a long time than when he is standing. Prolonged supine lying causes the body to slowly adapt to the low resistance. After the fracture has healed and the patient is standing or walking, the vascular resistance of the lower extremities returns to normal levels, but the vessels still have difficulty adapting to return flow under these conditions, and therefore swelling occurs. It is recommended that patients with swelling after 50 days of fracture should go to the hospital in time to have the cause of swelling clarified under the guidance of a specialist, and actively cooperate with the doctor to carry out follow-up treatment.