Flocculent material in the eye refers to an inflammatory reaction in the anterior chamber or vitreous clouding. Anterior chamber inflammation can be seen under slit lamp with flocculent clouding in the atrial fluid, along with the presence of anterior chamber inflammatory cells and anterior chamber flashing glow, which is typical of uveitis. Once the disease is diagnosed, early administration of hormonal type eye drops, as well as dilated pupils and nonsteroidal anti-inflammatory drugs is required. At the same time, the fundus is examined to determine the posterior aspect of the eye. This is a dangerous and recurrent disease that can lead to irreversible vision loss. In the presence of vitreous opacities, the patient’s subjective perception is that of dark shadows floating in front of his or her eyes, and an examination may reveal visible intravitreal flocculent material. For patients whose vision is not affected, there is no need for treatment. However, if the patient is inflammatory in nature or hemorrhagic in nature, consideration needs to be given to determining the cause and the site of the hemorrhage as soon as possible, as most will manifest with vision loss.