There is no most effective way for a child to have a fever in the middle of the night, and you need to choose physical cooling or medication according to the degree of fever to treat the child. 1. Physical cooling: children with fever in the middle of the night, parents should measure the temperature several times, if the temperature is below 38.5 degrees, the child’s mental state is good, you can first take the physical cooling methods, such as drinking more water, can replenish the body fluids, and promote the metabolism, is conducive to reduce fever. You can also use warm water to wipe the body, such as forehead, armpits, neck, groin and other parts of the body, is conducive to heat dissipation. 2. medication: if the physical cooling effect is not good, the temperature continues to rise above 38.5 degrees, you can follow the doctor’s instructions to use antipyretic drugs, such as ibuprofen, acetaminophen, etc. to reduce fever, and timely measurement of the child’s body temperature is back to normal. There are many reasons for the child’s fever, it is recommended to go to the hospital in time to check the blood routine, to clarify the cause of the disease, under the guidance of the doctor for medication.