Generally taking cold medicines does not affect antigen testing. The main effect of cold medicines is to reduce mucosal edema, which can relieve the patient’s symptoms, and generally have no effect on the virus itself. The viral content in the antigen test specimen will not change after taking cold medicine, so taking cold medicine will not affect the antigen test in general, but it is recommended to wait for the drug to be completely metabolized before taking the antigen test after taking cold medicine, so as to avoid affecting the test result due to the drug. However, if the patient has recently been vaccinated with the New Crown vaccine, the patient should be informed in time so as not to affect the results of the New Crown antigen test.