When it comes to the hypoglycemic drug metformin, I believe that many diabetic patients are very familiar with the effect of this drug in the treatment of diabetes is still very good, can effectively and quickly control the patient’s condition, reduce the patient’s physical discomfort, but many diabetic patients in the use of this drug will also appear some more uncomfortable situation, such as the use of drugs will appear after the diarrhea, chest tightness and other symptoms, for these Many patients can not tolerate the appearance of symptoms, then, metformin side effects, what are the adverse reactions? Metformin side effects: 1, the impact on the gastrointestinal: the drug will enter the patient’s blood after digestion and absorption of the gastrointestinal, in the process of digestion and absorption, will inevitably bring some impact on the gastrointestinal, such as bloating, abdominal pain, nausea, etc., if these symptoms, the patient is best not to take this drug. 2, lactic acidosis: after taking this drug, it will lead to the increase of lactic acid in the human body and a large amount of accumulation, if the body can not be discharged in time to decompose, it may cause acidosis, so this is also the patient needs to pay attention to the phenomenon. Metformin six contraindications: 1, people with kidney disease can not take this drug, because the drug metabolism is not through the liver, if the kidney function abnormalities in people taking this drug is likely to cause serious consequences. 2, people with liver disease is best not to take this drug, because the large amount of lactic acid produced by this drug will increase the burden on the liver, so take and this drug must maintain normal liver function. 3, people with stomach problems can not take this drug, this drug is still relatively large stimulation of the stomach, suffering from gastritis and other diseases are not suitable for taking this drug. 4, people suffering from intestinal diseases should be strictly prohibited to use this drug, the absorption of drugs is in the intestine, if the patient has enteritis and other diseases, it is easy to cause diarrhea and other symptoms. 5, people with blood disorders need to pay attention, if you can not take this drug is best not to use, in order to avoid adverse consequences. 6, people suffering from heart disease have a lot of contraindications when it comes to medication, this drug is one of them, the increase in lactic acid in the blood will affect the aggravation of heart disease. The above content is to introduce some adverse reactions caused by metformin drugs and people suffering from which diseases can not take this drug related knowledge, hope that through the above introduction can make people understand the safety of the use of drugs, but also hope that people in the treatment of disease do not abuse drugs, otherwise not only can not cure the disease, but also make the disease more serious, in the use of drugs, patients must be When using medication, patients must communicate with their primary care physician, choose some effective and less side effects of drugs, in the process of medication should also try to reduce the adverse effects of drugs.