Cell necrosis is the disruption of normal cellular metabolism caused by a variety of factors, resulting in altered cell morphology, leading to cell lysis and destruction. 1. There are more factors that cause cell necrosis, such as extreme chemical (strong acid, strong alkali, toxic substances, etc.), physical (radiation, high heat, etc.), biological (pathogens, etc.), or induced by other serious pathological factors. Necrotic cells release inclusions that cause an inflammatory response in the surrounding tissues of the body, while scarring forms during the healing process. 2. Cell necrosis can be divided into acute necrosis and chronic necrosis. Acute necrosis is the organism suddenly encountered damage caused by the destruction of cell structure and death, such as human tissue suddenly suffered a car accident; chronic necrosis of the death process is slow. Cellular necrosis is an important response of the organism to external pathological stimuli. Cells can eliminate the damage caused by pathological stimuli through their own death and through inflammation, but it may also induce related diseases.