Patients with advanced liver metastasis from lung cancer will experience pain in the liver area, which is the most common symptom of liver metastasis. More than half of the patients will show persistent swelling pain or dull pain, and the liver will also be enlarged, with uneven surface and limited bulging or fullness in the upper abdomen. Some patients may have a combination of peritoneal effusion and rapid increase of ascites, which may cause abdominal distension and loss of appetite. In addition, they will also show cachexia, progressive wasting, fever, loss of appetite, weakness, malnutrition, nausea and vomiting, etc.