The difference between hypertensive nephropathy and chronic nephritis mainly lies in the degree of urinary protein, the type of renal pathological damage, other target organ damage, treatment modality and so on. 1. Degree of urinary protein: the urinary protein of hypertensive nephropathy patients is usually <1.5g/d; the amount of proteinuria caused by chronic nephritis can be more or less, and the quantitative amount of 24-hour urinary protein can be within the normal range, or there can be a large amount of proteinuria exceeding 3.5g/d. 2. The type of renal pathological damage: hypertensive renal damage is mainly small arteriolar vitelliform lesions, which can involve renal tubular mesenchyme; while chronic nephritis can appear various pathological manifestations, such as mesangial cell hyperplasia, endothelial cell hyperplasia, basement membrane thickening and so on. 3. Other target organ damage: hypertensive nephropathy patients usually have cardiovascular, cerebrovascular and other target organ damage; while chronic nephritis patients do not necessarily have. 4. Treatment: Hypertensive nephropathy is based on the use of antihypertensive drugs to control blood pressure, such as nifedipine extended-release tablets, etc., usually do not need to use hormones and cytotoxic drugs; chronic nephritis can be used to lower the blood pressure, reduce urinary protein, etc., if the patient does not have obvious contraindications, but also the application of glucocorticosteroids and cytotoxic drugs, such as prednisone, cyclophosphamide and so on. All of the above medications should be used under the guidance of a doctor to avoid self-medication. Whether it is hypertensive nephropathy or chronic nephritis patients, it is recommended to go to the regular hospital in time, under the guidance of the doctor standardized treatment.