Vitiligo is a common acquired pigment loss skin and mucous membrane disease. Mild vitiligo usually can not be completely cured, but through reasonable treatment can make the patient’s symptoms better. Vitiligo is promoted by a variety of internal and external factors in the genetic background, patients appear autoimmune, oxidative stress and other aspects of dysfunction, leading to the destruction of melanocytes, causing pigment loss. As the cause cannot be completely eradicated, the disease cannot be completely cured. However, mild vitiligo can be treated with topical tacrolimus ointment and tacalcitol ointment, transplantation therapy, phototherapy and other ways to make the condition better and in remission. After the relief of the disease if the patient in daily life to maintain a regular routine, light diet, reduce skin irritation and so on can reduce the recurrence of vitiligo. The slight vitiligo patients should go to the hospital in a timely manner, under the guidance of the doctor to carry out regular treatment, the use of drugs need to follow the doctor’s instructions, to avoid further aggravation of the condition.