The tuberculin test is commonly used for tuberculosis screening, and blistering of the skin indicates a strong positive test, suggesting that active tuberculosis infection may be present. The tuberculin test is performed by injecting a tuberculin derivative intradermally and observing the skin reaction at the injection site 48-72 hours later. If there is no skin reaction, it suggests that there is no infection or within 4-8 weeks of the first infection and immunodeficiency; if a hard nodule of 5-9mm is formed, it suggests that there is previous tuberculosis infection or BCG vaccination; if the hard nodule is 10-15mm, it is moderately positive; if it is ≥15mm, or there are blisters or necrosis locally, it is strongly positive, suggesting that there is probably active tuberculosis infection, and sputum smear or chest CT is needed to clarify it. Tuberculin test localized skin blistering suggests the possible existence of tuberculosis infection, it is recommended to go to the hospital at the specified time for observation and further examination to clarify the existence of tuberculosis.