There are different types and stages of glaucoma, and the corresponding drug choices are different. For preclinical closed-angle glaucoma, prophylactic drops of 1% maurobronchioline can be used if surgery is not desired. For acute onset closed-angle glaucoma, Maohuozhuoxin eye drops should be administered once every 15 minutes, and after the IOP drops or when the pupil returns to normal size, the number of doses should be reduced and finally maintained three times a day. At the same time 20% mannitol intravenous rapid drip, oral acetazolamide 250mg each time, drops of 0.5% timolol eye drops. Glucocorticoid eye drops can be used to reduce inflammatory edema during the seizure period when congestion is obvious. For primary open-angle glaucoma, choose one kind of topical IOP-lowering drugs first, and use two or more IOP-lowering drugs when IOP cannot be controlled, such as trigonelline, timolol, piperidine, meclizine, suvetan, etc.