Signs of ankylosing spondylitis include lumbosacral pain and morning stiffness. The onset of ankylosing spondylitis is insidious and slow, and the early signs are lumbosacral pain, which is dull, obvious at night, and aggravated by prolonged sitting or exertion. Sacroiliac, groin, and buttock pain can also occur, mostly on one side, with intermittent episodes that can be relieved on their own. Morning stiffness, the morning after getting up feeling stiffness in the lower back, need to move the lumbar symptoms can be reduced. With the development of the disease pain can also be to the thoracic spine, cervical spine development. When the above symptoms occur, we should be alert to ankylosing spondylitis, and need to go to the orthopedic department or rheumatology department of the hospital for examination and further treatment.