Gastric cancer develops in the sinus department, which is mainly determined by the physiological structure of the stomach. Gastric sinus is at the lower part of stomach, near the outlet of stomach, and there are more mural cells in gastric sinus, which are cells producing gastric acid, so the content of gastric acid in gastric sinus is on the high side. In addition, the patient’s ulcers and the high level of stomach acid has a lot to do with, after the high level of stomach acid, the patient’s sinus ulcers are prone to occur, especially in the secondary Helicobacter pylori infection after the incidence will be higher. The ulcers in the gastric sinus may lead to cancerous ulcers or chronic atrophic gastritis, which mainly develops in the gastric sinus, and therefore may progress into gastric cancer over a long period of time.