Generalized anxiety disorder is a syndrome of persistent worry and anxiety about daily life events or thoughts that the person often recognizes as excessive and inappropriate, but cannot control. It is a chronic disorder and is the most common type of anxiety disorder. In the CCMD-3, generalized anxiety disorder refers to an anxiety disorder that is dominated by preoccupation and nervousness lacking clear objects and specific content, with significant autonomic symptoms, muscle tension and motor restlessness. Clinical manifestations and disease characteristics of generalized anxiety disorder: 1. Worry About 13% of patients with generalized anxiety disorder have anxiety as the main complaint, and patients are often in the worry and apprehension of being upset and having misfortune coming. This worry can involve all aspects of life, and the degree is more pronounced and lasts longer than the usual worry or concern. The worry is difficult to control and often has no specific cause or clear object. Some patients seem to have some cause, but their level of worry is clearly disproportionate to the reality of the situation. 2. Somatic symptoms Patients with generalized anxiety disorder mostly have obvious somatic symptoms, with pain and fatigue being more prominent. Somatic symptoms can involve respiratory, cardiovascular, digestive, neurological, urinary and other systemic systems, mainly due to increased sympathetic nerve activity. Clinical manifestations include panic, chest tightness, shortness of breath, dizziness, excessive sweating, facial flushing or pallor, dry mouth, feeling of obstruction in swallowing, stomach discomfort, nausea, abdominal pain, bloating, diarrhea, frequent urination, pain in various areas, and muscle tension. Some patients may experience sexual dysfunction such as impotence, premature ejaculation, menstrual disorders and lack of libido. 3. Patients with motor restlessness manifest as rubbing their hands and feet, walking back and forth incessantly, and an increase in purposeless small movements. Some patients show lip, tongue or limb tremors, or even voice tremors, walking difficulties. 4. Increased sensitivity Patients are often overly alert to external stimuli, easily irritated by trivial matters, temper tantrums, complaints, inattentive to work and conscious memory loss. Sleep disorders are more prominent, often manifested as difficulty sleeping, dreamy, easy to wake up, and even nightmares. Some patients visit the clinic with the main complaint of sleep disorder. 5, depression about 2/3 of patients combined with depression, generalized anxiety disorder is often considered a risk factor for depression. The risk of suicide is significantly higher in patients with comorbid depression, and this phenomenon is relatively common in middle-aged and elderly people. Patients with generalized anxiety disorder have a high co-morbidity rate with other anxiety disorders. About 1/4 of patients have panic disorder, and some also have fear and obsessive-compulsive symptoms. Patients also often have comorbid alcohol and substance dependence, and some have comorbid somatic disorders such as peptic ulcers, hypertension, and diabetes. Patients with co-morbidities often have more impaired social functioning, need to seek more medical help, and are less responsive to treatment, making them a high consumer of medical resources.