The liver is an organ in the body that is mainly responsible for metabolic functions and plays a role in de-oxidation, storage of liver sugar, secretory protein synthesis, etc. The liver also produces bile in the digestive system. A large and hard liver is a problem with the liver. There are many diseases that cause a large and hard liver, and the most toxic disease is liver cancer. A typical symptom of liver cancer is a large and hard liver. Liver cancer refers to malignant tumors occurring in the liver, including primary liver cancer and metastatic liver cancer, and most people refer to primary liver cancer in their daily life. Primary liver cancer is one of the most common malignant tumors in clinical practice. It is a high incidence in China, and generally more men than women. Liver cancer can be caused by many reasons. Epidemiological statistics show that areas where hepatitis B is prevalent are also areas with high incidence of liver cancer, and people who have had hepatitis B have as much as 10 times higher chance of developing liver cancer than those who have not had it. Long-term clinical observation shows that hepatitis, cirrhosis, and liver cancer are a trilogy that constantly migrates and evolves. As the saying goes, “drinking alcohol hurts the liver”, drinking alcohol is not the direct cause of liver cancer, but its role is similar to that of a catalyst, which can promote the occurrence and progression of liver cancer. The more alcohol you drink, the more serious your fatty liver will become, which will lead to liver fibrosis, cirrhosis and liver cancer. If hepatitis patients then drink a lot of alcohol, it will greatly accelerate the formation and development of cirrhosis and promote the occurrence of liver cancer. Meanwhile, the occurrence of liver cancer is closely related to living habits. Long-term consumption of moldy food, food containing nitrosamines and selenium deficiency of trace elements are also important factors to promote liver cancer. In addition, the occurrence of liver cancer is also related to genetic factors and parasitic infections.