Neck long acanthosis nigricans is mainly through general treatment, drug treatment. Acanthosis nigricans is a relatively common autosomal dominant hereditary disease, it may also be caused by obesity, drugs and other factors induced by these factors, such as obesity caused by, pay attention to adjusting dietary habits, low-salt and low-fat diet, and do more physical exercise, weight control, generally will gradually ease. In addition, need to take medication, generally need to take oral vitamin A, and need to long-term oral, and with the local use of cod liver oil, hydroquinone cream ointment and other coated, can help to reduce hyperpigmentation relieve symptoms. Neck long acanthosis nigricans should be timely consultation, with the doctor to take treatment to alleviate the condition. Drugs need to follow the doctor’s instructions to use, do not self-medication.