Symptoms of acanthosis nigricans include deepening of skin color, dryness and roughness, appearance of warty skin cells, itching of the skin and so on. 1. Deepening of skin color: the skin of patients with acanthosis nigricans is initially gray or brownish-yellow, and as the disease continues to progress, the melanin deepens and the boundary between the lesion and the surrounding skin becomes unclear. 2. Dry and rough skin: in the early stage of the disease, the skin surface of the patient is dry and rough, and when the disease is aggravating, the skin will be thickened. 3. Warty skin: velvety papillomatous lesions will appear in the skin folds, dirty gray to gray hyperplasia will cause corns, and there are different degrees of hyperkeratosis, and finally warty skin. 4. itchy skin: in the late stage of the disease, when the disease is serious, the skin lesions will appear localized infiltration, the patient will feel itchy symptoms. It is recommended to go to the hospital in time for the above symptoms, and under the guidance of the doctor to carry out regular treatment as soon as possible to alleviate the uncomfortable symptoms.