Toothpaste can reduce swelling, generally according to the specific circumstances of the patient’s local injury, objective analysis. First, if the patient’s local skin inadvertently by mosquito bites, accompanied by mild itching and swelling, then you can rub toothpaste externally, because toothpaste contains mint and other ingredients, can play a better anti-inflammatory, anti-swelling effect, relieve local itching and swelling. Second, if the patient due to serious trauma, resulting in local skin tissue rupture, accompanied by active bleeding and obvious swelling of the limb, then the external rubbing toothpaste can not play a significant swelling effect, but may cause infection of the trauma. The wound should be thoroughly cleared with hydrogen peroxide, vital iodine and saline, covered with sterile gauze locally, and the tissue exudation can be reduced by local icing. In the later stage, hot aman pack should be applied externally, blood circulation and blood stasis ointment should be applied externally, and oral medications such as Mai Zhi Ling can reduce local swelling and pain and promote early wound healing.