Quinolone and cephalosporin antibiotics are used for pyelonephritis. Pyelonephritis is a kind of urinary tract infection, which is mainly caused by bacterial infection, and the urine routine of patients with pyelonephritis shows positive for occult blood, leukocyte count, positive for nitrites, and the blood routine shows an increase in the count of neutrophils and leukocytes. For pyelonephritis, antibacterial and anti-inflammatory treatment should be given, and urine culture and drug sensitivity test should be done first, according to the results of urine culture and drug sensitivity test to clarify the causative species and choose the appropriate antibiotics, so that the treatment will be more effective. Commonly used antibiotics for pyelonephritis patients are quinolones and cephalosporins, quinolone antibiotics include levofloxacin injection, ofloxacin injection, etc. Cephalosporin antibiotics include ceftriaxone sodium, cefoperazone sodium sulphadiazine sodium, etc. Traditional Chinese medicines can also be applied in conjunction with the treatment, such as the application of bamboo leaves brewed as a substitute for tea in order to clear the heat and clear the drenching.