The main drugs for nerve pain relief include the following: First, for a patient with mild nerve pain, we can give non-steroidal anti-inflammatory drugs, such as fotarine orally. If a patient with moderate to severe neuralgia is treated with nerve-nourishing drugs, such as vitamin B1, B12 intramuscular injections or oral nerve-nourishing drugs. Second, antiepileptic drugs such as gabapentin, carbamazepine, or oxcarbazepine can be given to relieve pain. Third, Pregabalin can also be given orally to relieve pain. But oral pregabalin, carbamazepine, oxcarbazepine must be noted that patients have an early adverse reaction of dizziness, so the dose should be gradually increased from a small dose to reduce the patient’s discomfort. Fourth, if the pain is accompanied by sleep disorders, we can also combine the use of amitriptyline or duloxetine for oral administration, the main drugs to relieve neuralgia include the above.