Lung cancer is one of the most dangerous malignant tumors to human health and life, and it has become the number one cause of death in many countries, and China is one of the more prominent countries. 1.35 million new cases of lung cancer and 1.18 million deaths were added worldwide in 2002, ranking first among all malignant tumors. Due to the huge number of smokers, the increasingly serious environmental pollution, the development of industry and the aging of population, the incidence and mortality of lung cancer in China have been increasing significantly in recent years. According to the information provided by the National Cancer Control Office of the Ministry of Health, the number of lung cancer cases in China increased by 120,000 from 2000 to 2005, among which, the number of male lung cancer patients increased from 260,000 in 2000 to 330,000 in 2005, and the number of female lung cancer patients increased from 120,000 to 170,000 in the same period. At present, the incidence rate of lung cancer in China is increasing 26.9% annually. If effective control measures are not taken in time, it is expected that by 2025, China will reach 1 million lung cancer patients and become the world’s largest lung cancer country. Lung cancer not only has a high incidence and mortality rate, but also has a trend of younger age of incidence, with the current peak incidence age of lung cancer being 51-60 years old, which is significantly earlier than the previously reported 71-80 years old. It has also been reported that the average age of lung cancer incidence in China decreases by one year every 5 years. In addition to the trend of younger age of incidence, the gender difference in the incidence of lung cancer is also decreasing. In the 1970s, the ratio of male to female lung cancer in developed countries was 4~5:1, and even as high as 10:1 in some cases, while the male to female ratio in China was 2.1~2.3:1. The incidence rate of male lung cancer in North America has been decreasing for more than 30 years, but the incidence rate of female lung cancer has been increasing gradually. In the past, the male to female sex ratio ranged from 1.70 to 3.56:1, but in recent years, the male to female sex ratio has been decreasing due to the higher growth rate of lung cancer incidence among women than men in some regions. In many regions, lung cancer has become the number one malignancy in terms of incidence and death among women. There are also significant ethnic and geographic differences in lung cancer incidence rates. An Israeli study compared the risk of lung cancer among Israeli Jews and Arabs with that of whites and blacks in the United States. In our country, due to the wide geographical area and differences in social, cultural and economic development, there are also significant geographical differences in lung cancer incidence rates. First of all, there are differences in incidence rates: urban incidence rates are significantly higher than rural incidence rates, and the larger the city, the higher the incidence rate of lung cancer. 100,000), Yangcheng County (9.0/100,000), and Linzhou (9.2/100,000). Secondly, the difference in growth rate: in recent years, the growth rate in rural areas is higher than that in urban areas. Due to the rapid rural urbanization process, the incidence rate of lung cancer in some more economically developed rural areas, such as Jiashan, Zhejiang, Qidong, Jiangsu, and Linqu, Shandong, has approached some urban levels, while the incidence rate of lung cancer in men in some cities, such as Shanghai and Dalian, has stabilized or declined, which may be related to population aging.