Calluses on the hands can be repaired by scraper, medication, physical therapy to solve. 1. Scraper repair: the palm of the hand immersed in warm water, soak the soft stratum corneum, the use of a sharp scraper to scrape off the epidermis keratinized callus can be, need to pay attention to a time can not be scraped too deep, to avoid scratching the normal skin caused by infection. 2. medication: can be applied in the callus parts of the compound lactic acid cream, urea ointment, salicylic acid, etc., to play the role of softening the keratin to promote the role of shedding. 3. Physical therapy: cryotherapy can be used to remove, the use of a certain temperature of liquid nitrogen on the callus, accelerate the peeling of the callus. Calluses on the hands is a very common phenomenon, it is recommended to avoid the frequent use of a posture labor, to reduce the repeated friction of a certain part. The above drugs need to be used in accordance with medical advice. If there is any discomfort, it is recommended to go to the hospital in time.