Changing medication after surgery for anal disease plays a very important role in the healing of the wound. If the medication is not changed properly, it can not only prolong the course of the disease, but also cause postoperative recurrence. In order to prevent postoperative bleeding, patients are usually allowed to relieve stool 24 hours after surgery, take a sitz bath afterwards, and then change the medication. Thereafter, it is best to change the medication once a day. If the number of drug changes is too many, the cotton ball repeatedly rubbing the wound surface during the drug change can cause damage to the new granulation tissue and the crawling epithelial tissue, but will prolong the wound healing time. If the number of dressing changes is too small or if the dressing is not changed after surgery, the wound will easily form a pseudo-healing and will need to be treated by surgery again. In addition, if the wound granulation is too vigorous and the epithelial tissue crawls poorly, the wound may not heal for a long time. Therefore, postoperative patients are advised to change the medication moderately, once a day. If there is too much postoperative secretion or too much pus draining from the paranal abscess after excision, the medication can be changed 2-3 times a day to prevent the secretion from irritating the perianal skin and causing perianal eczema.