The five-year survival rate of middle and late stage colon cancer, which are clinically referred to as Stage III and Stage IV, is relatively low, at 40% and 5% respectively. However, due to the individual variability of the tumor, long-term survival is also possible if patients choose active treatment. The survival period of colon cancer in middle and late stages cannot be generalized and needs to be analyzed on a case-by-case basis. 1. Intermediate stage of colon cancer: usually there are only lymph node metastasis, or there are high-risk factors but no distant metastasis, the five-year survival rate of this kind of colon cancer is relatively high, and according to domestic and foreign reports, it may reach 60%-70%. 2. advanced colon cancer: for example, there are distant metastases, and the most common colon cancers are liver metastases and lung metastases, and it used to be thought that patients with metastases have very poor survival rate and bad treatment effect. However, in recent years, after a lot of international and domestic practical researches, it has been proved that part of the treatment effect is better, for example, for isolated liver metastasis, patients can achieve 50% or even higher survival rate in 5 years through appropriate treatment. There are also some multiple metastases, which can be treated by chemotherapy and combined with local radiofrequency therapy and surgery, and the limited 5-year survival rate or 3-year survival rate can also reach about 30%. The prognosis is also different between left half colon cancer and right half colon cancer, and the prognosis of left half colon cancer will be better.