GERD is a benign disease that does not usually affect life expectancy. If serious complications occur, life expectancy may be affected, but there is some variation in the impact of different complications on survival time. GERD is caused by esophageal reflux disease and esophageal mucosal damage due to excessive exposure or exposure of the esophagus to gastric juices. Common symptoms are acid reflux and heartburn. Atypical symptoms include discomfort in the upper abdomen, painful swallowing, coughing and sore throat, which often appear about one hour after a meal. In general, GERD does not affect a person’s life and can usually be completely cured with regular treatment and dietary adjustments. If GERD is complicated by Barrett’s esophagus, further development may result in the formation of esophageal adenocarcinoma, but this usually takes years or even a decade. If gastric contents reflux into the airway, resulting in blockage of the airway and causing asphyxia, it may lead to death immediately if not treated immediately. Gastroesophageal reflux disease requires regular treatment, medication as prescribed by the doctor, and regular review of gastroscopy, which usually does not affect normal life expectancy.