Both renal pelvis cancer and bladder cancer belong to urological tumors, clinically, there is no one seriousness, most of the patients have better prognosis if treated early and timely. Most of the patients have better prognosis if treated early and timely. With the same staging and grading, renal pelvis cancer is more serious. Renal pelvis cancer refers to a kind of malignant tumor of kidney that occurs in renal pelvis, and the cause of the disease is mainly related to the environment, chemical carcinogens, smoking and other factors. Patients mainly manifest painless hematuria, lumbar pain, emaciation and other symptoms. The tumor malignancy of renal pelvis cancer is relatively low, and most of the patients generally have better prognosis after actively cooperating with treatment. Bladder cancer is a malignant tumor disease originated from the bladder. The cause of the disease is not clear for the time being, and it is mostly related to heredity, environment, smoking, chemical carcinogens and other factors. Patients mainly manifest painless hematuria, urinary urgency, difficulty in urination and other symptoms. The prognosis of bladder cancer is mostly related to tumor stage and treatment plan, and the overall recurrence and metastasis rate of the disease is high. Renal pelvis cancer and bladder cancer have the same staging and grading, and renal pelvis cancer is still more serious. The standard surgery for renal pelvis cancer is partial cystectomy of the renal ureter, while transurethral cystectomy of the bladder tumor is an option for most bladder cancers. The severity of renal pelvis and bladder cancers depends mainly on the type of tumor and whether it can be detected at an early stage and treated early and promptly.