Two plus white blood cells, usually referring to elevated levels of white blood cells, mostly indicate the presence of infection in the organism being examined, and have different meanings in different specimens. For example, the presence of two plus white blood cells in the urinalysis generally indicates a recent urinary tract infection. If there is no change in lymphocytes, it indicates that a bacterial urinary tract infection may have occurred, which may be accompanied by symptoms such as urinary frequency, urinary urgency and painful urination, and requires antiseptic and anti-inflammatory treatment. Quinolones are commonly used clinically. If they occur in women’s leukorrhea analysis, it indicates the presence of unclean vaginal environment and vaginitis, and vaginal douching with metronidazole topical sterilization is generally recommended. The presence of two plus white blood cells in the stool routine may indicate the presence of enterocolitis. In addition, the presence of two plus white blood cells in pleural and ascites tests may also indicate abdominal and thoracic inflammation, which requires further identification and treatment of the cause.