Numbing is the common name for anesthesia medication, and it is recommended to drink alcohol after three days after taking anesthesia medication. Also, drinking alcohol is an unhealthy behavior and it is recommended to abstain from it. There are more commonly used anesthesia drugs, such as: lidocaine, procaine, bupivacaine, sevoflurane, desflurane, sodium thiopental, ketamine, etomidate, etc. The two main types of anesthesia include local anesthesia and general anesthesia. After the anesthesia drugs are administered, the drugs are slowly metabolized from the body when the medication is stopped. Normally, it takes about 48 hours for the drug to be fully metabolized. Drinking alcohol too soon may enhance the effects of the anesthetic drug, thus inducing a dangerous event. To ensure safety, patients are advised to think about drinking alcohol three days after stopping the medication. In addition, drinking alcohol is an unhealthy behavior that may cause damage to the body’s tissue organs, especially the liver. Long-term and heavy drinking can easily induce conditions such as alcoholic liver and fatty liver, which can cause damage to the patient’s body. Therefore, patients are advised to quit drinking as much as possible.