Hepatitis B virus DNA (dna) 7.33 x 10 to the second power is not considered very serious. Hepatitis B virus DNA replication number is mainly used to assess the amount of hepatitis B virus in the body, to determine how infectious a patient with hepatitis B or a carrier of hepatitis B is, and also to assess the effectiveness of treatment with antiviral medication and to determine whether oral anti-hepatitis B virus medication is needed for treatment. Clinically, the simple finding of an increased number of hepatitis B virus DNA replication, also need to be combined with the patient’s age, liver function, liver ultrasound, family history, etc.; if the patient’s age is greater than 30 years old, there is a family history of cirrhosis, liver cancer, need to start antiviral treatment program in a timely manner. For patients with an increased number of hepatitis B virus replicates, it is recommended to consult the Department of Infection of a regular hospital and consult a specialist for guidance.