The preferred antidotes for organophosphorus pesticide poisoning are depot phosphoramidite, chlorophosphoramidite and atropine, of which depot phosphoramidite and chlorophosphoramidite are also called cholinesterase rekindling agents, which have a certain effect on the early formation of phosphorylated cholinesterase. If the time is too long or chronic organophosphorus pesticide poisoning, these two detoxifying drugs are not too effective. Generally 4-6 hours to give intramuscular injection once, atropine is also the earlier the application of the better, are mainly intravenous push, usually according to the condition can be in about 10-20min push once, or directly given intravenous drip to maintain the best effect.