Nucleic acid mixed collection and single collection in the collection and delivery mode, scope of application, price and other aspects of the differences. 1. Collection and delivery methods: Nucleic acid single collection refers to a person’s nucleic acid nasal swab or throat swab samples placed in a separate sampling tube for delivery and testing, and if the results are positive, they can directly correspond to the patient. Mixed sampling means that the nasal or pharyngeal swab samples of multiple individuals are placed in the same sampling tube for testing, and if the result is positive, it is necessary to re-test the individual in this tube to determine the positive patient. 2. Scope of application: Nucleic acid single-collection is applicable to high-risk areas, hospital workers and other high-risk groups, as well as airports, railway stations and other cross-provincial and cross-border crowd gathering places. Mixed collection of nucleic acids is suitable for low and medium risk areas, which is more efficient and saves costs and resources. 3. Price: Generally, the price of single-collection is higher than that of mixed-collection. Nucleic acid single collection and mixed collection are suitable for different situations, and different regions, different times and different needs can choose the appropriate way to conduct nucleic acid testing.