Cranial defect is now a relatively common craniofacial disorder, and many risk factors in life may lead to cranial defect, such as traffic accidents, falling objects, craniofacial surgery and so on. Cranial defect brings great harm to the body, so it is necessary to have cranial repair as soon as possible. The hazards of skull defect: 1. It brings a lot of inconvenience to labor, work and study, and always need to be careful of the head, especially the skull defect is injured again. Once injured, even a minor trauma may lead to a serious traumatic brain injury or a large intracranial hemorrhage and endanger life because of the lack of skull protection. Based on this, many young adults, have to give up their original jobs and many students have to avoid extracurricular activities and physical education classes. At the same time, it brings heavy psychological burden to myself and family members. 2, cranial defect often defect in the role of atmospheric pressure, the scalp will be invaginated, long-term, will cause softening of brain tissue at the defect, necrosis, and even ventricular penetration deformity, affecting the recovery of neurological functions, such as the recovery of limb motor function, the recovery of intelligence, intellectual development, etc.. In some patients, the symptoms may worsen, and even the degree of disability may increase. Once again, softening foci are one of the root causes of seizures, which may lead to re-seizures in those who originally did not have epilepsy, or may cause frequent seizures in those who originally had occasional seizures, and require lifelong medication. 3, cranial defect will bring many people cranial defect syndrome, the light manifestation is dizziness, dizziness, the heavy manifestation is headache, things especially the defect, wash, haircut have pain and discomfort, high temperature, sun exposure can lead to headache, dizziness and brain damage. In the long run, it will inevitably affect daily life, study and work. 4.Large skull defect, especially the frontal part, will seriously affect the appearance. Cranial defect is very harmful to human body, so it is necessary to perform cranial repair as soon as possible. Of course, the material of repair is also very important. Currently, we are using the latest polyetheretherketone material, also called PEEK, to better solve these problems. This PEEK material can be shaped in three dimensions for a precise fit. In addition, it is a bionic material that is highly compatible with autologous cranial bone and is comparable to autologous cranial bone in terms of elasticity, heat transfer, stiffness, and stability, especially for pediatric patients, and can better adapt to the growth and development of autologous cranial bone.