Glimepiride is a sulfonylurea hypoglycemic agent, which lowers blood glucose primarily by stimulating insulin secretion. Glimepiride is best taken shortly before or during breakfast. If breakfast is skipped, it is taken shortly before or during the next main meal. If you miss a dose of the medication, you should not take a larger dose to avoid hypoglycemia. Side effects of glimepiride may cause hypoglycemia, so if a patient experiences recurrent hypoglycemia, he or she should see a doctor to have the dosage adjusted promptly. If the patient’s weight, lifestyle changes, or there are obvious factors that increase hypoglycemia and hyperglycemia, you should also consider adjusting the dosage, then you should go to the doctor to adjust the dosage, do not adjust the dosage on your own, and always follow your doctor’s instructions to use the medication.