When doctors diagnose and treat diabetic patients, they often prevent certain complications such as diabetic foot. But now I also found a problem, we often tell people that diabetic patients have a difficult wound healing characteristics, but rarely tell you what are the specific causes. Here, our diabetic foot specialist gives you a brief explanation of several factors: First, in the state of high blood sugar, the ability of white blood cells to phagocytosis and kill harmful bacteria will be reduced, making the wound more prone to bacterial infection problems, and sometimes the infection will expand to the surrounding tissues of the wound, causing the wound to become larger and more difficult to heal, the occurrence of diabetic foot is related to this process. Second, for people with high blood sugar, poor blood sugar control can cause excessive aggregation of platelets in the wound. The platelet aggregation is good for wound hemostasis, but in fact is not conducive to wound healing. Third, or the cells in the body, are macrophages. Macrophages produce angiogenic factors and collagen-stimulating factors, etc., which are important substances to promote wound healing. But when blood sugar rises, the number of macrophages will fall, causing a series of complex reactions the end result is a wound is difficult to heal. Of course, this point may not be well understood. Fourth, there is the problem of vascular lesions. Especially for patients with long disease duration, old age, poor blood sugar control, often accompanied by peripheral vascular disease of the lower limbs, specifically manifested as atherosclerosis, stenosis or even occlusion of the blood vessels, resulting in a decrease in oxygen saturation of the lower limbs, so that the wound will not get sufficient blood supply, slowing down the healing rate or even not healing. Fifth, there is the problem of neuropathy. Many patients with lower limb numbness, weakness, pain, decreased sensitivity and other symptoms, most of them are caused by lower limb neuropathy. Neuropathy can cause weakening of the lower limbs to external stimuli, the appearance of wounds without being aware of them, and secondary wound injuries that are not easily detected, all of which can affect the healing of wounds. Some nerve functions, such as motor nerve, can help muscle tissue stretching, which I think is still helpful for wound healing. But after the lesion is gone, the healing will also be affected. Of course, in addition to improper care and disposal, the patient’s overall health status, blood pressure and blood lipids, psychological and other factors can all have some impact on the patient’s wound healing. Therefore, we must be comprehensive in our daily science, so that patients can do a thorough prevention and care methods, the wound healing is still very fast.