Tearlessness occurs when the lacrimal glands are not developed congenitally, or due to an acquired autoimmune system disorder that disrupts lacrimal secretion, resulting in the desire to cry without tears. Tearlessness is an eye disease that cannot be cured, and patients can only rely on medicated ointments to improve symptoms or use special moisturizing glasses to avoid water evaporation. Chronic inflammation affects the muscular nerve of the lacrimal duct, which reduces the contraction of the duct, and the inflammatory infiltration around the duct weakens the duct wall, and the inflammatory stimulation induces an increase in tear secretion, resulting in passive dilation of the duct and the formation of a cyst. The patient has no tears or few tears. The diagnosis can be made based on the clinical manifestations.