The world’s first “test tube baby”, Louise Brown, was born on July 25, 1978 at Oldham Hospital in Lancashire, England, which was a great miracle in the history of human fertility. This attracted the attention of scientists from all over the world, and since then, many countries have followed suit, and “test tube babies” have become increasingly popular. Since then, many countries have followed suit, and “test tube baby” has become increasingly popular. “Test tube baby” technology has been developed from scratch all over the world, and has brought good news to countless infertile families. However, “IVF” is also very “picky”, what kind of diseases can people consider using “IVF” to get pregnant? (I) Tubal lesions 1. Tubal obstruction, severe tubal adhesion, fluid accumulation, which is not effective after surgical treatment or estimated to be unable to restore the function of the fallopian tubes. 2.Congenital or secondary tubal loss or tubal sterilization without the possibility of reopening. 3.Other obstacles caused by tubal “egg collection”. (B) Ovulation disorders: repeated unruptured follicle luteinization, ineffective drug-induced ovulation, and polycystic ovary syndrome to promote follicular development is not ideal, and it is difficult to control the number of follicular development. (iii) Endometriosis Endometriosis combined with infertility or the ineffectiveness of other complementary treatments for conception. (iv) Male factors Low sperm, weak sperm or high sperm deformity rate, low volume and poor quality of male semen can be artificially selected for high quality sperm. (v) Congenital diseases Some congenital cervical diseases or cervical injuries. (vi) Reproductive function reserve Women can be frozen and stored when there is a possibility of damage to ovarian function due to disease treatment or other reasons. (vii) Immune Infertility Immune infertility and other unexplained infertility. Nowadays, many people think that doing test tube is like buying something, give money to take goods, don’t want to treat, or treat less a little difficult to think of doing test tube. But ignored the most critical part: 1, advanced age is definitely not an indication for “IVF! 2, “test tube baby” can 100% solve the problem of eggs and sperm can not meet, but can not solve the quality of eggs and sperm. 3. The success rate of IVF is not that high, and it is not guaranteed with money. Poor quality of fertilized eggs will naturally increase the chance of IVF failure. We only see that IVF is favored among female celebrities, and many senior celebrities and the general public believe that with IVF, the pregnancy age can be postponed indefinitely. The key to IVF success is a woman’s age. As a woman ages, the number of follicles in her ovaries decreases and the quality of her oocytes declines, which especially affects the grade of her embryos. The success rate of IVF is lower in older patients. Nowadays, we advocate natural conception, and it is better for both husband and wife to undergo the same investigation and treatment. In conclusion, IVF is not a panacea, and we cannot rely on it too much. The only way is to have children at the right age and to conceive naturally and healthily.