Why was bleomycin discontinued?

Bleomycin is Bleomycin Hydrochloride for Injection, which has not been discontinued and is still in clinical use. The main components of Bleomycin Hydrochloride for Injection are Bleomycin A2, Bleomycin B2. It is mainly used for the treatment of squamous carcinoma of the head and neck, esophagus, skin, cervix, vagina, vulva, penis, Hodgkin’s disease and malignant lymphoma, testicular carcinoma and carcinomatous pleural effusion. The drug currently exists only in injectable form and there is no oral formulation. When using the drug, common adverse reactions are manifested as cough, chest pain, skin pigmentation at the joints, nausea, vomiting, etc. Occasionally, serious reactions such as dyspnea and anaphylaxis are seen. When a serious adverse reaction occurs, the doctor should be informed and relieved. In addition, it is forbidden to use the drug if you are allergic to it or if you suffer from chickenpox, and it should be used with caution in elderly patients over 70 years of age, patients with impaired lung function, impaired liver and kidney function, pregnant women, and children. The drug should be used under the supervision of a doctor.