Heart-kidney disharmony (heart fire, kidney yin deficiency, dysfunction of the physiology of the heart and kidneys) is a Chinese medicine term, which is derived from the doctor’s identification through the four diagnostic information, and there is no test for heart-kidney disharmony. Heart-kidney disharmony is a TCM term that refers to a pathological phenomenon in which the physiological coordination of the heart and kidneys is out of whack, mostly due to kidney yin deficiency, where the yin essence cannot be carried upward, and thus the heart’s fire is over-exuberant and fails to descend. Heart-kidney disharmony may be caused by excessive worry, depression, prolonged illness, or uncontrolled sexual intercourse, and usually manifests symptoms such as panic, anxiety, insomnia, forgetfulness, dizziness, tinnitus, and lumbar and knee pain and weakness. Heart and kidney disorders can be treated with Huanglian and Agaricus soup, Jiaotai pills, etc. In addition, eat a light diet and learn to regulate your own emotions. If there are symptoms of heart and kidney disorders, it is recommended to consult a hospital in time, under the guidance of a professional physician, so as not to delay the condition.