There is no fastest way to eliminate perianal swelling, according to the specific cause of the choice of appropriate treatment, the more common are hemorrhoids, anal fissure, perianal abscess and other diseases. 1. Hemorrhoids: Hemorrhoids are congested or bruised and enlarged venous plexus of the anal canal or lower end of the rectum, resulting in anal swelling, bleeding and other symptoms. Can be used externally hemorrhoid cream or suppositories and other drugs to improve the acute attack period can also be warm water or medication sitz bath, such as 1:5000 potassium permanganate solution sitz bath, swelling and anti-inflammatory, for the more serious symptoms need to go to the hospital for surgical treatment. 2. Anal fissure: anal fissure is a rupture or tear of the skin of the anal canal, in the acute episodes will also have the symptom of swelling, you can apply topical lidocaine gel, nitroglycerin ointment and other medications, but also can be surgical treatment, including anal flap technology, anal sphincter cut off surgery. 3. Perianal abscess: this is a purulent infection caused by anal gland obstruction, there will also be swelling, perianal abscess once diagnosed, should be carried out as soon as possible abscess incision and drainage surgery, may also need oral antibiotic drugs to control the infection, such as amoxicillin, cephalexin and other drugs. Perianal swelling, it is recommended to go to the hospital for a detailed examination, for the cause of the disease under the guidance of the doctor to choose the appropriate treatment, the above medication should be used under the guidance of a doctor, to avoid self-medication, causing adverse consequences.