Many patients and friends know that over the years many large and small hospitals have departments like gastroenterology, cardiovascular medicine, neurology, general surgery, hepatobiliary surgery, orthopedic surgery and so on, but when it comes to GERD centers, you may be very unfamiliar, now, through this website, briefly introduce you to GERD. Gastroesophageal reflux disease (GERD) is a condition in which the contents of the stomach and duodenum flow back into the esophagus causing symptoms such as heartburn, which can lead to reflux esophagitis (RE), and damage to the tissues adjacent to the esophagus such as the throat and airway. Gastroesophageal reflux disease is very common in Western countries, and about 7%-15% of the population has GERD. The incidence increases with age, with the peak incidence age being 40-60 years old, and there is no difference in incidence between men and women, but there are more men than women with GERD (2-3:1). The prevalence of GERD in Beijing and Shanghai is 5.77%, and that of GERD is 1.92%, which is lower than that in western countries, and the disease is also milder. A significant proportion of patients with GERD may have no endoscopic manifestations of esophagitis, and this type of GERD is also known as endoscopically negative GERD or non-erosive reflux disease (NERD).