Lobar fibrosis should accurately refer to pulmonary fibrosis, which can be treated with medication, surgery, etc. depending on the condition. 1. Drug treatment (1) Glucocorticoid is the leading drug in the treatment of pulmonary fibrosis, which can inhibit the inflammatory reaction and slow down the process of pulmonary fibrosis, and common drugs include methylprednisolone and so on. (2) Immunosuppressants can reduce the body’s immune response, but the frequent use of serious side effects, usually used when glucocorticosteroids are not able to achieve a better therapeutic effect, and patients with poor liver function, pregnant women are prohibited, common drugs include azathioprine and so on. (3) Anti-fibrotic drugs include pirfenidone, nidanib, colchicine, N-acetyl cysteine and so on. (4) Antacid drugs are usually used when the patient suffers from gastroesophageal reflux disease, and common medicines include omeprazole, ranitidine and so on. 2. Surgery: If the patient’s condition is serious, lung transplantation can be considered as prescribed by the doctor. 3. Other: patients can also under the guidance of the doctor for oxygen therapy, pulmonary rehabilitation, palliative care and so on. It is recommended that patients go to regular hospitals in time and follow the doctor’s instructions for symptomatic treatment.