Hepatitis B surface antigen of 600 or more indicates that the organism may be infected with the hepatitis B virus. Hepatitis B surface antigen is the protein shell encoded by the genetic material of the hepatitis B virus. Positive hepatitis B surface antigen is an important sign of hepatitis B virus infection, and the normal quantitative value of hepatitis B surface antigen is less than 0.5 units. Hepatitis B surface antigen 600 or more has been significantly higher than the normal value range, suggesting that acute hepatitis B virus infection in the early stage, latent stage or chronic hepatitis B virus carriers, etc., the specific situation needs to be combined with the hepatitis B five specific analysis. Hepatitis B surface antigen test alone can not accurately reflect viral replication, infectiousness and prognosis. When the surface antigen of hepatitis B is over 600, it is recommended to carry out further diagnosis and antiviral treatment under the guidance of doctors, and can take drugs such as entecavir and lamivudine for treatment.