Irbesartan Hydrochlorothiazide works after 1 hour of taking it, and the effect can last for 24 hours. Irbesartan hydrochlorothiazide contains Irbesartan and hydrochlorothiazide two ingredients, belongs to the compound preparation, Irbesartan’s main role is to inhibit angiotensin II receptor, hydrochlorothiazide belongs to the diuretic, the two together can increase the therapeutic effect of the drug, and at the same time, can prevent the adverse effects of low potassium. Irbesartan and hydrochlorothiazide can play a role in lowering blood pressure in one hour after taking the drug, the half-life of the drug is about 11 hours, so the efficacy of this drug can last for about 24 hours, and can be taken once a day. Adverse effects of Irbesartan Hydrochlorothiazide include flu-like symptoms, dizziness, thirst, electrolyte disorders, allergy to the components of the drug, severe renal impairment, pregnancy and breastfeeding women are prohibited. Abnormal blood pressure, you should actively seek medical attention, take the drug as prescribed by the doctor, avoid making unauthorized choices to avoid adverse consequences.