Infections can lead to destruction or excessive consumption of platelets, which may result in lower platelets. Platelets are a component of the body’s blood that prevents bleeding and stops bleeding. When the body is infected with a bacterial or viral infection, it can cause destruction or depletion of platelets, causing a decrease in platelet count. Bacterial infections that cause thrombocytopenia are commonly associated with beta-hemolytic streptococcal infections, resulting in upper respiratory tract infections and pneumonia. Under the stimulation of bacteria, the patient’s immune cells secrete large amounts of IgA, IgE and other inflammatory factors, forming IgA immune complexes, which will destroy platelets and cause platelet reduction. Some viruses such as measles, chickenpox, rubella, etc., the virus itself will destroy platelets, but also induce the body’s immune response, produce platelet antibodies, further destruction and consumption of platelets. Infection can cause platelet lowering, it is recommended to seek timely medical treatment, standardized treatment.