Bile duct stones are divided into intrahepatic bile duct stones and extrahepatic bile duct stones. Depending on the severity of the symptoms and differences in location, medication or surgery can be used to relieve pain. 1, drug treatment 1, intrahepatic bile duct stones: if the intrahepatic bile duct stones appear painful symptoms, the first should be given timely anti-inflammatory, antispasmodic, analgesic treatment, the main drugs are anti-inflammatory and cholagogic tablets, scopolamine, etc., to be further assessed after the symptoms improve. Generally, intrahepatic bile duct stones are asymptomatic isolated stones, and if the number of stones is small, regular observation and follow-up can be considered. 2. Therefore, in the early stage, fasting and water fasting must be given in a timely manner, combined with appropriate drugs to relieve pain, such as anti-inflammatory and cholagogic tablets, eliminated scopolamine, ursodeoxycholic acid, etc. Surgical treatment: If intrahepatic bile duct stones are accompanied by pain, chills, high fever and other symptoms, and if the conservative treatment is not effective or the symptoms recur, surgical treatment should be considered. The main purpose of surgical treatment is to remove the lesion, unblock the drainage, correct the stricture and remove the stone. This situation is very serious and requires timely patency and drainage. The treatment options for extrahepatic bile duct stones include retrograde cholangiopancreatography (ERCP), minimally invasive stone extraction, and bile duct excision, which can be performed directly through the gastrointestinal tract to remove stones from the bile ducts, avoiding surgery. Patients with unsuccessful ERCP stone extraction, or those with certain anatomical abnormalities, should consider choledochotomy for stone extraction, or consider laparoscopic or robot-assisted surgical treatment with smaller incisions and faster recovery.