Stroke is a disease caused by the deficiency of vital energy, diet, emotion, strain and internal injury, which leads to the disorder of Qi and blood, resulting in wind, fire, phlegm and stasis, resulting in the paralysis of brain veins or blood overflowing outside the brain veins as the basic pathogenesis, with sudden fainting, paraplegia, distorted mouth and tongue, speech or no speech, and numbness of the partial body as the main clinical manifestations. Stroke is a serious threat to human health, with high mortality and disability rates. In the prevention, treatment and rehabilitation of this disease, Chinese medicine has more significant efficacy and advantages. The “Five-in-One Acupuncture” is a set of effective acupuncture and moxibustion treatment for stroke rehabilitation that has been summarized by our department after years of clinical practice. The therapy integrates the five acupuncture methods of waking up the brain and opening up the orifices, Bi’s head inch acupuncture, head acupuncture, body acupuncture and neck acupuncture in one, which can play the role of waking up the brain and opening up the orifices, opening up the ligaments and atrophy, and treating both the symptoms and the root cause. Through rehabilitation, most stroke patients can reduce or avoid disability and regain the ability to take care of themselves or even work.