Colposcopic biopsy has the potential to miss certain cervical cancer diagnoses, and serial pathological sections of cervical tissue after cold knife conization for a comprehensive and accurate diagnosis. In case of missed cervical cancer, a direct hysterectomy alone would be extremely damaging to the patient’s body and would require another open surgery to perform standard radical cervical cancer surgery. CIN II to III and cold knife conization is recommended. After cold knife conization, it is necessary to keep bowel movement and vulva clean, walk less and not to carry heavy objects. If there is a possibility of hemorrhage, infection, cervical canal stenosis and cervical os adhesions after cold knife conization, timely visit to the hospital doctor can be dealt with. Whether to cut the uterus further after cold knife conization is handled differently in different cases at different ages. It is recommended to consult the doctor